Biocompatibility and Stability of Polysaccharide Polyelectrolyte Complexes Aimed at Respiratory Delivery
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چکیده
منابع مشابه
Biocompatibility and Stability of Polysaccharide Polyelectrolyte Complexes Aimed at Respiratory Delivery
Chitosan (CS) and chondroitin sulfate (CHS) are natural polymers with demonstrated applicability in drug delivery, while nanoparticles are one of the most explored carriers for transmucosal delivery of biopharmaceuticals. In this work we have prepared CS/CHS nanoparticles and associated for the first time the therapeutic protein insulin. Fluorescein isothiocyanate bovine serum albumin (FITC-BSA...
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Among different polymers, chitosan, the N-deacetylated product of the polysaccharide chitin, is gaining increasing importance in medical and pharmaceutical applications due to its good mucoadhesion and absorption enhancing ability. Moreover, chitosan shows the ability to form hydrogels able to control the rate of drug release from the delivery system as well as protect the drug from chemical an...
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There has been a growing interest in the design and development of polymeric microspheres as controlled release systems for drugs and antigens. Different types of polymers have been used to design biodegradable polymeric microparticles. Poly(lactic-co-glycolic) acid (PLGA) microspheres have been extensively investigated because of their biocompatibility and biodegradability. PLGA has been appro...
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ژورنال
عنوان ژورنال: Materials
سال: 2015
ISSN: 1996-1944
DOI: 10.3390/ma8095268